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The cathinones are a group of compounds that are based on the chemical structure of cathinone — a naturally-occurring alkaloid from the khat plant (Catha edulis).
Mephedrone is an incredibly potent substance with similar effects to MDMA, although with markedly less empathogenic properties. Like other synthetic cathinones, it also has a strong stimulant aspect.
As a designer drug, 4-MMC appears to be most popular in Europe, especially in the UK. However, since 2010 it has been made strictly illegal in most first-world countries.
Cathinones like 4-MMC and MDPV are known to be highly addictive and relatively prone to causing serious health consequences. Anyone thinking about taking 4-MMC should approach the drug with extreme caution and respect.
What Are The Effects of 4-MMC?
Mephedrone carries all the signature trademarks of its class — it’s incredibly potent and has a strong emphasis on its stimulant effects. This drug still maintains a considerable amount of the hallucinogenic and empathogenic qualities, not unlike MDMA.
Rat studies have identified the usual physiological effects associated with stimulants, such as increased motor activity and hyperthermia [1]. However, when it comes to the subjective effects, a person might feel while on 4-MMC, we’re forced to utilize designer drug forums.
These subjective descriptions are obviously lacking in scientific rigidity, but they’re usually quite adept at sketching out the effects associated with a drug, as well as pointing out the differences with other substances. Also, because of 4-MMC’s considerable popularity, the sample size is quite large, and thus, the results are more accurate.
The following effects have been associated with 4-MMC:
- Physical effects — Stimulation, Body high, Physical euphoria, Vibrating vision, Tactile enhancement,
- Cognitive effects — Cognitive euphoria, Thought acceleration, Increased music appreciation, Ego inflation, Disinhibition, Empathy and sociability enhancement, Time distortion, Motivation enhancement, Anxiety suppression, Compulsive redosing, Increased libido, Wakefulness
- After Effects — Anxiety, Cognitive fatigue, Depression, Irritability, Motivation suppression, Thought deceleration, Wakefulness
4-MMC’s particular style of stimulation is quite forceful. It often makes users want to run around, dance, and otherwise engage in physical activity. At high doses, it may even become difficult or impossible to keep still. This stimulation makes 4-MMC a popular choice at raves and festivals.
The empathogenic component of 4-MMC is definitely present, but users have described it as less permanent than that of MDMA or 2C-B. Increased libido, however, is a notoriously powerful effect with 4-MMC.
Analysis of the ratio of dopamine and serotonin indicated mephedrone was preferentially a serotonin releaser, with a ratio of 1.22:1 (serotonin vs. dopamine) [2]. Normally, serotonin release is pharmacologically associated with empathogenic and, depending on the specific receptors, psychedelic effects.
These results would suggest that 4-MMC is more similar to a drug like MDMA than to cocaine. However, user results always highlight the strong character of its stimulation.
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